主な著作物(医学論文)

最新の高血圧治療. 上久保啓太: 薬局新聞 2594:8-9, 2003.

生活習慣病のインターネットサイト「健康倶楽部」−反省と展望. 上久保啓太: 糖尿病ケア IT革命(医歯薬出版) 206-7, 2002. 

Early caritod atherosclerosis in type 2 diabetes mellitus: relation to hypertension and dyslipidemia. Keita Kamikubo, Toru Ogawa, Sin-ichi Kawachi, Keiko Nakagawa: 岐阜県医師会医学雑誌 13:55-64, 2000.

難治性高脂血症に著明な心膜液貯留を来した甲状腺機能低下症の1例. 上久保啓太、石森正敏、中村重徳: 日本臨床内科医会会誌 15:33-6, 2000.

動脈硬化症の予防に向けて. 上久保啓太: プラクティス(日本糖尿病協会/医歯薬出版) 17:200-1, 2000.

Hypokalemic periodic paralysis associated with hypophosphatemia in a patient with hyperinsulinemia. Ogawa T and Kamikubo K: Am J Med Sci. 318:69-72, 1999

Spontaneous healing of pancreatic abscess after fistulization to the duodenal bulb. Kawachi S, Ogawa T, Ukita M, Shiroko J, Kawase Y, Adachi S, Kametani M, Kamikubo K: Am J Med Sci 314:44-46, 1997

糖尿病における頸動脈硬化の危険因子. 上久保啓太、小川 徹、川地慎一: 岐阜県医師会医学雑誌 10:157-164, 1997.

閉経後糖尿病症例における腰椎骨塩密度. 小川 徹、川地伸一、上久保啓太: 日本臨床内科医会会誌 12:14-17,1997.

耐糖能悪化をきたした偽性アルドステロン症の1例. 澤田道夫、川地慎一、小川 徹、上久保啓太:日本臨床内科医会会誌 11:268-71, 1997.

Risk factors for carotid atherosclerosis in Japanese diabetics. Kamikubo K, Ogawa T, Kawachi S: Eur Atheroscl Soc 1996.

Renal refractoriness to phosphaturic action of parathyroid hormone in a patient with hypomagnesemia. Mihara M, Kamikubo K, Hiramatsu K, Itaya S, Ogawa T, Sakata S: Int Med 34:666-9, 1995.

脂質異常の病態と治療. 上久保啓太、小川 徹、平松佳子、板谷聡実:岐阜県内科医会雑誌 9:49−53、1995.

Carbamylphosphate synthetase 活性の低下を伴い多彩な合併症を示した成人型シトルリン血症の1例. 河瀬晴彦、棚橋 忍、白子順子、上久保啓太、亀谷正明、小林圭子、佐伯武頼:肝臓 36:302−7、1995.

Possible gliclazide-induced water retension with azotemia. Kamikubo K,Takami R, Suwa T, Sugiyama A, Horibe N, Sakata S: Int Med 33:163-4, 1994.
Silent thyroiditis developed during alpha-interferon therapy. Kamikubo K, Takami R, Suwa T, Kawase Y, Shiroko J, Kametani M, Tokimitsu N, Sakata S: Am J Med Sci 306:174-6, 1993.

甲状腺亜全摘術3年後に発症した副甲状腺機能低下症の一例. 高見和久、上久保啓太、柴田敏朗、大橋伸一、坂田茂樹:総合臨床 42:413−5, 1993.

きわめて少量のグリチルリチン製剤により著明な横紋筋融解をきたした偽性アルドステロン症の1例. 高見和久、上久保啓太、諏訪哲也、高見利恵子、坂田茂樹:日本臨床内科医会会誌 8:195−8, 1993.

Differential regulation of multiple c-erbA expression by thyrotropin, insulin and insulin-like growth factor I in rat thyroid FRTL-5 cells. Kamikubo K, Nayfeh SN, Chae CB: Mol Cell Endocrinol 84:219-225, 1992.

A case of rheumatoid arthritis associated with silent thyroiditis. Sakata S, Nagai K, Shibata T, Kamikubo K, Tokimitsu N: J Endocrinol Invest 15:377-80, 1992.

The deoxyribonucleic acid regions involved in the hormonal regulation of thyroglobulin gene expression. Lee NT, Kamikubo K, Chai KJ, Kao Lr, Sinclair AJ, Nayfeh SN, Chae CB: Endocrinology 128:111-8, 1991.

Thyroid hormone metabolism and nuclear binding in Gunn rats. Komaki T, Sakata S. Kamikubo K, Matsuda M, Nakamura S, Ogawa T, Sato H, Keino H, Kashiwamata S, Miura K: J Endocrinol Invest 14:409-15, 1991.

Similar nuclear factors mediate stimulation of rat thyroglobulin gene transcription by thyrotropin and insulin-like growth factor-I. Kamikubo K, Chai KJ, Nayfeh SN, Chae CB: Mol Endocrinol 4:2021-9, 1990.

Thyroxine binding to human serum albumin immobilized on Sepharose and effects of non-protein albumin-binding constituents. Kamikubo K, Sakata S, Nakamura S, Komaki T, Miura K: J Protein Chem 9:461-5, 1990.

Evidence for disulfidebonds in membrane-bound and solubilized opioid receptors. Kamikubo K, Murase H, Murayama M, Matsuda Y, Miura K: J Neurochem 50:503-9, 1988.

グルココルチコイド:構造(製剤)とその効力. 上久保啓太、三浦清 ステロイドホルモン 228-37, 1988.

Coupling of adrenal medullary opioid receptors to islet-activating protein-sensitive GTP-binding proteins. Kamikubo K, Murase H, Niwa M, Miura K, Nozaki M, Tsurumi K: Life Sci 40:1791-7, 1987.

Solubilization of adrenal medullary opioid receptors. Kamikubo K, Murase H, Murayama M, Miura K: Endocrinol Japon 34:897-901, 1987.

Phospholopid/Ca++-dependent protein kinase activity in human parathyroid adenoma. Ishizuka T, Kajita K, Kamikubo K, Komaki T, Miura K, Nagao S, Nozawa Y: Endocrinol Japon 34:965-8, 1987.

Adrenal medullary opioid receptors are linked to GTP-binding proteins, pertussis toxin substrates. Kamikubo K, Murase H, Niwa N, Miura K, Nozaki M, Tsurumi K: Progress in Opioid Research 129-132 US Department of Health and Human Service, 1987.

Varying expression of opioid receptors and GTP-binding proteins in human pheochromocytomas. Kamikubo K, Murase H, Niwa M, Miura K, Miura Y, Satoh T, Tomita A: Progress in Opioid Research 133-6 US Department of Health and Human Service, 1987.

副腎髄質オピオイド受容体に関する研究 1 副腎髄質オピオイド受容体とオピオイドの結合. 村瀬 寛、上久保啓太、村山正憲、安田圭吾、鶴見介登、三浦清:日本内分泌学会雑誌  63:727-40, 1987.

副腎髄質オピオイド受容体に関する研究 2 副腎髄質オピオイド受容体とGTP結合蛋白質の連関. 村瀬 寛、上久保啓太、村山正憲、安田圭吾、鶴見介登、三浦清:日本内分泌学会雑誌  63:741-51, 1987.

乳漏無月経症候群の母親から出生した13-trisomy 児の1例. 今井龍幸、上久保啓太、安田圭吾、三浦清:日本内科学会雑誌 76:78-82, 1987.

Opioid and non-opioid binding of B-endorphin to bovine adrenal medullary membranes. Kamikubo K, Murase H, Niwa M, Miura K, Nozaki M, Tsurumi K: Regulat Pept 15:155-62, 1986.

Microcomputer-based nonlinear regression analysis of ligand-binding data: application of Akaike's information criterion. Kamikubo K, Murase H, Murayama M, Miura K: Japan J Pharmacol 40:342-6, 1986.

A case of total thyroxine-binding globulin deficiency with Graves's disease: fluctuations of plasma triiodothyronine/thyroxine ratio. Kamikubo K, Kojima N, Yamakita N, Miura K: Japan J Med 25:186-90, 1986.

A case of Graves's disease with anti-triiodothyronine antibodies. Sakata S, Komaki T, Nakamura S,Kamikubo K, Takakuwa K, Kametani M, Tokimitsu N, Miura K: Endocrinol Japon 32:181-8,1985.

An improved method for the detection of thyroid hormone autoantibodies (THAA) in serum. Nakamura S, Sakata S, Komaki T, Kamikubo K, Yasuda K, Miura K: Autoimmunity and the Thyroid, 401-2, Academic Press 1985.

Two cases associated with thyroid hormone autoantibodies. Komaki T, Sakata S, Nakamura N, Kamikubo K, Miura K, Kametani M, Tokimitsu N: Autoimmunity and the Thyroid, 403-4, Academic Press 1985.

Effects of sulfonylurea drugs on the interaction between thyroxine binding globulin (TBG) and triiodothyronine. Sakata S, Nakamura N, Kamikubo K, Komaki T, Miura K: Current Topics in Clinical and Experimental Aspects of Diabetes Mellitus, 291-4, Elsevier 1985.

副腎皮質ステロイド薬の種類、薬物動態と作用機序. 上久保啓太、安田圭吾、五島英一、三浦清 内科 55:404-10 1985.

副甲状腺疾患. 上久保啓太、北田雅久、今井龍幸、村山正憲、安田圭吾、三浦清 臨床検査 29:543-51, 1985.

Theoretical consideration of the effects of dilution on estimates of free thyroid hormones in serum. Kamikubo K, Komaki T, Nakamura S, Sakata S, Yasuda K, Miura K: Clin Chem 30:634-6, 1984.

Serum thyroglobulin concentration in healthy subjects: absence of age- and sex-related differences. Nakamura S, Sakata S, Minamori Y, Komaki T, Kojima N, Kamikubo K, Yasuda K, Miura K: Endocrinol Japon 31:93-8, 1984.

Serum thyroglobulin concentration in normal pregnancy. Nakamura S, Sakata S, KOmaki T, Kojima n, Kamikubo K, Miyazaki S, Yasuda K, Tsukada H, Shiraki S, Miura K: Endocrinol Japon 31:675-9, 1984.

Morphine inhibits depolarization-dependent calcium uptake by synaptosomes. Kamikubo K, Miura K, Fujimura H: Eur J Pharmacol 32:149-50, 1983.

Kinetics of hepatic thyroxine 5'-deiodinase. Kamikubo K, Nakamura S, Horike S, Sakata S, Yasuda K: Acta Endocrinol 103:558-61, 1983.

A solid phase radioimmunoassay for the detection of anti-insulin antibodies. Sakata S, Imai T, Kamikubo K, Nagai K, Okuyama M, Sato H, Kashiwamata S, Miura K: Endocrinol Japon 30:23-8, 1983.

Genetic control of mouse antibody production to human thyroglobulin. Aihara Y, Sakata S, Nakamura S, Kamikubo K, Tarutani O, Yamada S, Tadokoro I, Okuda K: J Immunogenetics 10:325-31, 1983.

Age- and sex-related differences of serum thyroxine binding globulin in healthy subjects. Kojima N, Sakata S, Nakamura S, Kamikubo K, Okuyama M, Miura K: Acta Endocrinol 104:303-6, 1983.

In vivo and in vitro effects of two insulin-antagonistic peptides in the urine of patients with congenital generalized lipodystrophy. Okuyama M, Challoner DR, Kikuchi M, Imai T, Takeda N, Sakata S, Kamikubo K: Current and Future Therapies with insulin 305-10, Excerpta Medica 1983.

Diabetic gangrane in Japan. Okuyama M, Nagai K, Miyazaki S, Kosaka J, Kamikubo K, Miura K, Matsutomo K, Inada K: Tohoku J Exp Med 141:583-6, 1983.

125I-protein A を用いた抗ヒト thyroglubulin 抗体の固相法 radioimmunoassay の検討. 坂田茂樹、中村重徳、上久保啓太、小嶋範子、奥山牧夫、三浦清、佐藤浩、柏俣重夫、樽谷修:日本内分泌学会雑誌 59:815-23, 1983.

橋本病による若年性甲状腺機能低下症の姉妹例に認められた抗T3、抗T4自己抗体に関する検討 第三報 抗rT3自己抗体. 中村重徳、小嶋範子、上久保啓太、坂田茂樹、安田圭吾、三浦清:日本内分泌学会雑誌 59:973-982, 1983.

橋本病、甲状腺機能亢進症における抗甲状腺ホルモン自己抗体の検討. 中村重徳、村山正憲、小嶋範子、上久保啓太、坂田茂樹、安田圭吾、三浦清:日本内分泌学会雑誌 59:1597-607, 1983.

免疫吸着剤を用いた血清TBGと甲状腺ホルモンとの相互作用の研究(1)健常人と妊婦でのTBGとT4のKa値の検討. 坂田茂樹、小嶋範子、堀家誠一、中村重徳、上久保啓太、小牧卓司、三浦清、近藤芳明、春名光晶、伊藤一男:日本内分泌学会雑誌 59:1256-64,1983.

抗甲状腺ホルモン抗体産生機序に関する研究2. ヒトthyroglobulinを抗原としたマウスでの抗体産生の免疫応答遺伝子レベルでの調節. 坂田茂樹、相原幸雄、奥田研爾、中村重徳、上久保啓太、小牧卓司、小嶋範子、樽谷修、三浦清:日本内分泌学会雑誌 59:1729-37, 1983.

麻薬拮抗性鎮痛薬Butorphanolおよびその主代謝産物の依存性形成能. 丹羽雅之、野崎正勝、上久保啓太、藤村一、門田利人: 日本薬理学会誌 82:451-63, 1983.

Elimination of GTP biphasic regulation of synaptosomal adenylate cyclase by manganese and solubilization. Kamikubo K, Miura K, Fujimura H: Japan J Pharmacol 32:893-902, 1982.

橋本病による若年性甲状腺機能低下症の姉妹例に認められた抗T3、抗T4自己抗体に関する検討 第二報 合成L−T4治療による影響. 中村重徳、伏見勝正、上久保啓太、坂田茂樹、安田圭吾、奥山牧夫、三浦清: 日本内分泌学会雑誌 58:1527-43, 1982.

Inhibition of adenylate cyclase by GTP and its modification by opiate receptor in rat caudate nucleus. Kamikubo K, Nozaki M, Fujimura H: Japan J Pharmacol 31:175-84, 1981.

Chemical features for opiate agonist and antagonist. Nozaki M, Kamikubo K, Niwa M, Fujimura H, Imai E, Suzuki Y, Hori M: Endogenous and Exogenous Opiate Agonists and Antagonists 9-12 Pergamon Press,1980.

A role of lipid in opiate-receptor interaction. Nagaoka S, Hasegawa J, Nozaki M, Kamikubo K, Sogami M, Fujimura H, Imai E, Hori M: Endogenous and Exogenous Opiate Agonists and Antagonists 271-4 Pergamon Press,1980.
 

略歴 主な著作物
健康倶楽部